I bought Friendly Biology for next year. I chose it over Guesthollow, because Friendly Biology looks more traditional. My dd likes textbooks and simplicity.
Guesthollow is more of a unit study approach, which both of us feel overwhelmed by. That said, I may incorporate pieces of Guesthollow, like the Knex DNA.
I like Friendly Biology’s textbook and worksheets better. For my next dd, I will either use the videos or add Biology 101 dvds, as well as some real books and extras.
I am switching out and adding to the labs, using ACE lab videos, Apologia, and The Illustrated Guide to Home Biology Experiments.